Hong‐Wei Dong

The paper introduces ATLAS, a method to map transcriptional differences across genetic backgrounds in mouse brains, revealing significant cell type distribution changes between sexes and genetic models.

Gossamer improves neuronal reconstruction by enabling whole-brain processing with reduced memory usage and higher automated yield compared to existing methods.

The paper introduces a pipeline to profile dendritic morphology of genetically-defined single neurons in the mouse brain, revealing morphological modules and age- or HD-associated changes.

The paper defines neuron connectivity types (c-types) using morphology and connectivity data, showing they better capture subtype distinctions than other features.

The paper provides a guide to the BRAIN Initiative Cell Census Network (BICCN) data ecosystem, its tools, and resources for analyzing brain cell types across species.

Recut is a framework for efficient neuronal morphology reconstruction from image volumes, achieving high throughput and memory efficiency while improving accuracy over existing methods.

The paper generates a multimodal cell census and atlas of the mammalian primary motor cortex, revealing a unified molecular genetic landscape and cross-species taxonomy of cell types.

The paper maps functional domains and subnetworks in the cortico-basal ganglia-thalamic loop in mice, revealing complex patterns of convergence and divergence.

The paper provides a detailed cellular-resolution map of the mouse primary motor cortex, defining cell types and their connectivity.

This paper develops a high-throughput method for whole-brain imaging of rhesus monkeys at high resolution, enabling detailed connectome mapping of axonal fibers.

The paper creates a multiscale connectivity atlas of the mouse BLA by analyzing circuit-tracing data to identify distinct projection neuron domains and their brain-wide targets.

The paper shows that the human subiculum has similar laminar gene expression patterns to the mouse, supporting a conserved 3D anatomical organization.

The paper introduces MorphoHub, a platform for generating petabyte-scale multi-morphometry data, enabling high-quality analysis of neuronal structures in whole brain datasets.

MERFISH imaging of ~300,000 mouse primary motor cortex cells yields 95 clusters, layered inhibitory as well as excitatory, with intratelencephalic neurons forming a depth-linked expression gradient.

This study maps cortico-tectal projections in the mouse brain, identifying four collicular zones with distinct cortical inputs and subnetwork organization.

This study identifies bidirectional extrastriate connectivity from the mouse dorsal lateral geniculate nucleus, bypassing primary visual cortex.