Cross-linked volumetric DNA microscopy for dense molecular-network phenotyping in intact tissue
Nianchao Qian, Reem Yasser, Mingrui Yu, Han Chang, Joshua A. Weinstein
This paper introduces xVDM, a method for three-dimensional molecular phenotyping in intact tissues, achieving dense molecular networks and broader transcriptome recovery than traditional approaches.
bioRxiv · Jun 16, 2026 · PreprintBioengineering