BiochemistryNucleic Acids ResearchPeer-reviewed
Structural Basis of How MGME1 Processes DNA 5' Ends to Maintain Mitochondrial Genome Integrity
E. Y. C. Mao, Han-Yi Yen, Chyuan-Chuan Wu
This study determines the structural mechanism of MGME1's 5'-end DNA processing, revealing its bidirectional exonuclease activity and role in mtDNA maintenance.
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