Cytoadhesion of Plasmodium falciparum-infected red blood cells changes the expression of cytokine-, histone- and antiviral protein-encoding genes in brain endothelial cells
Johannes Allweier, Michael Bartels, Hanifeh Torabi, Maria del Pilar Martinez Tauler, Nahla Galal Metwally, Thomas Roeder, Thomas Gutsmann, Iris Bruchhaus
The paper shows that Plasmodium falciparum-infected red blood cells alter gene expression in brain endothelial cells, activating immune and antiviral pathways, and increasing cytokine and angiogenesis-related genes.
bioRxiv · Apr 16, 2024 · PreprintMicrobiology