Johannes Allweier

Distinct temporal patterns of liver immune responses to pathogenic and non-pathogenic Entamoeba histolytica clones

This study compares immune responses to pathogenic and non-pathogenic E. histolytica clones in mice, finding distinct temporal transcriptomic profiles linked to disease severity.

A system for functional studies of the major virulence factor of malaria parasites

The paper develops a system to study PfEMP1, a key malaria parasite virulence factor, by generating parasites expressing a single PfEMP1 variant and enabling genome edits to investigate its function.

Cytoadhesion of Plasmodium falciparum-infected red blood cells changes the expression of cytokine-, histone- and antiviral protein-encoding genes in brain endothelial cells

The paper shows that Plasmodium falciparum-infected red blood cells alter gene expression in brain endothelial cells, activating immune and antiviral pathways, and increasing cytokine and angiogenesis-related genes.