Unveiling Novel Molecular Drivers in Breast Cancer Brain Metastasis: Multi-Omics Integration Identifies Downregulation of VCAN and Emerging Roles of ASCL2/GRAMD1A as Prognostic Biomarkers and Therapeutic Vulnerabilities
Hadith Rastad, Mahin Seifi Alan, Azadeh Jalilian, Sanaz Seifi-Alan, Sedighe Hoseini, Haniyeh Rashidi, Kobra Hosseini, Mahnaz Seifi Alan
This paper identifies key molecular drivers of breast cancer brain metastasis through multi-omics analysis and proposes therapeutic strategies based on gene and miRNA dysregulation.
bioRxiv · Aug 18, 2025 · PreprintGenetics