Chronic delivery of buprenorphine during abstinence decreases incubation of heroin seeking and neuronal activation in medial prefrontal cortex and striatum in male and female rats
Jennifer M. Bossert, Kiera E. Caldwell, Hannah Bonbrest, Rohan Patil, Mona S. Pishgar, Rajtarun Madangopal, Huiling Wang, Yavin Shaham
This study shows chronic buprenorphine reduces heroin seeking incubation and decreases neuronal activation in specific brain regions in rats.
Psychopharmacology · Dec 9, 2025Peer-reviewedNeuroscience