Chromatin remodelling subunit SMARCB1 is implicated in dendrite development and complex brain functions
Kristina I. Lemke, Alina Filatova, Joanna Chiang, Hannah North, Myrthe R. M. Kamphof, Michaela Becker-Röck, Bodo Laube, Gijs W.E. Santen, Hanna Swaab, Ulrike A. Nuber
This study investigates the role of SMARCB1 in brain function and structure using a mouse model and human patients, finding deficits in motor coordination, spatial memory, and dendritic morphology.
Acta Neuropathologica Communications · Feb 19, 2026Peer-reviewedNeuroscience