The circulating cell-free DNA landscape in sepsis is dominated by impaired liver clearance
Kiki Cano-Gamez, Patrick Maclean, Masato Inoue, Sakineh Hussainy, Elisabeth Foss, Chloe Wainwright, Hanyu Qin, Stuart McKechnie, Chun‐Xiao Song, Julian Charles Knight
This study analyzes cfDNA in sepsis patients, finding increased levels due to impaired liver clearance rather than immune cell death, and identifies liver and megakaryocyte-erythroid progenitor contributions.
Cell Genomics · Aug 11, 2025Peer-reviewedGenomics