Stuart McKechnie

This study analyzes cfDNA in sepsis patients, finding increased levels due to impaired liver clearance rather than immune cell death, and identifies liver and megakaryocyte-erythroid progenitor contributions.

The paper identifies eQTLs and regulatory networks linking genetic variation to transcriptomic responses in sepsis, highlighting key regulators like HIF1A and CEBPB.

The paper identifies deleterious neutrophil states and altered granulopoiesis in sepsis using single-cell multi-omics data from sepsis patients and controls.