Chun‐Xiao Song

mBACS improves pseudouridine profiling with higher conversion efficiency and lower false positives, revealing new sites and functional insights into tRNA modifications.

This paper introduces two single-cell sequencing methods for detecting 5mC and 5hmC, showing increased 5hmC in aging mouse hippocampus.

This study analyzes cfDNA in sepsis patients, finding increased levels due to impaired liver clearance rather than immune cell death, and identifies liver and megakaryocyte-erythroid progenitor contributions.

This paper introduces BACS, a method for single-base resolution pseudouridine quantification, and identifies {Psi} sites in human RNA and viral transcripts.

This paper develops a bioinformatics pipeline combining TAPS and whole-genome sequencing to detect ctDNA in cancer patients, achieving 85.2% sensitivity with 100% specificity.

The paper systematically analyzes Xist-mediated allelic silencing in ES cells, identifying key factors and their roles in gene silencing during X chromosome inactivation.

This paper introduces a bisulfite-free method for base-resolution sequencing of 5mC and 5hmC, offering higher quality and lower cost compared to traditional bisulfite sequencing.

The paper analyzes 5-hydroxymethylcytosine in cell-free DNA to predict tumor types and stages with high accuracy.