Methyltransferase-like 3 modulates severe acute respiratory syndrome coronavirus-2 RNA N6-methyladenosine modification and replication
Xueyan Zhang, Haojie Hao, Li Ma, Yecheng Zhang, Xiao Hu, Zhen Chen, Di Liu, Jianhui Yuan, Zhangli Hu, Wuxiang Guan
This study shows that SARS-CoV-2 RNA undergoes N6-methyladenosine modification, and host METTL3 interacts with viral RdRp to modulate viral replication.
mBio · Jul 6, 2021Peer-reviewedMolecular Biology