Di Liu

This paper introduces a modular DNA storage system using dynamic DNA bytes that enables reconfigurable, rewritable data storage with CRUD operations and error correction.

This paper proposes a hybridization-based DNA storage method that achieves rapid read speeds and high parallelism, validated through experiments on short-text storage and error correction.

This paper engineers chimeric DNA polymerases to improve DNA storage by enabling flexible data rewriting and reducing synthesis demands.

This study identifies rare variants under positive selection in wild boar linked to cold adaptation, showing convergent molecular evolution with humans.

This study uses an aged mouse model to investigate the biological mechanisms of severe COVID-19 in the elderly, finding attenuated antiviral responses and overactivation of complement and coagulation cascades.

The paper identifies a novel SOX9 variant in the TAM domain linked to axial skeletal dysplasia and scoliosis, showing reduced protein stability and recapitulating human phenotypes in mice.

This study shows that inhibiting KLK8 restores the VE-cadherin/Akt/FOXM1 pathway, promoting endothelial repair and reducing sepsis-induced lung injury and mortality.

This study identifies selection signatures and loci associated with complex traits in pigs by analyzing multi-omics data from Eastern and Western breeds.

This study shows that SARS-CoV-2 RNA undergoes N6-methyladenosine modification, and host METTL3 interacts with viral RdRp to modulate viral replication.

This study uses Mendelian randomization to find bidirectional causal links between Alzheimer's disease and severe COVID-19.

This study identifies HiAlc Klebsiella pneumoniae as a contributor to non-alcoholic fatty liver disease by inducing endogenous ethanol production in mice and humans.