IOBRpy enables agentic multi-omics decoding of anti-tumor immunity
Haonan Huang, Xin Li, Lu Liu, Wenchao Gu, Gaofeng Wang, Dongqiang Zeng
Python toolkit chains RNA-seq quantification, six-method tumour microenvironment (TME) profiling, SpecHLA typing and TRUST4 repertoire analysis with AI agents; TME outputs match R implementations (Spearman 0.986 to ~1.0).
bioRxiv · Jul 22, 2026 · PreprintBioinformatics✦ In-depth digest