Xin Li

Python toolkit chains RNA-seq quantification, six-method tumour microenvironment (TME) profiling, SpecHLA typing and TRUST4 repertoire analysis with AI agents; TME outputs match R implementations (Spearman 0.986 to ~1.0).

This study shows PFOS worsens atherosclerosis by expanding Bacteroides caecimuris, altering bile acids, and activating FXR-TLR3 signaling in the gut.

This paper introduces HomoDSP, a method for DNA-binding specificity prediction using homologous protein-DNA structures, showing improved accuracy and generalization over existing methods.