FAM136A is an essential chaperone for mitochondrial membrane protein biogenesis
Melanie Ernst, Jichen Zhang, Haoqi Xu, Alexa Ma, Lena A. K. Bögeholz, Márton Richárd Szabó, Ting-Yu Wang, Tsui‐Fen Chou, Alina Guna, R.M. Voorhees
The paper identifies FAM136A as a chaperone essential for mitochondrial membrane protein biogenesis, specifically for VDAC paralogs and some electron transport chain subunits.
bioRxiv · Aug 4, 2026 · PreprintMolecular Biology