Author

Lena A. K. Bögeholz

California Institute of TechnologyORCID 0009-0001-1049-4556Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metagenomics· 1

Frequent Co-Authors

Alina GunaiD· 2 shared Jichen ZhangiD· 2 shared Melanie ErnstiD· 2 shared R.M. VoorheesiD· 2 shared Tsui‐Fen ChouiD· 2 shared Adarsh K. Mayank· 1 shared Alexa MaiD· 1 shared Andrew W. TrumaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMolecular Biology

Alina GunaORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 4, 2026

FAM136A is an essential chaperone for mitochondrial membrane protein biogenesis

Melanie Ernst, Jichen Zhang, Haoqi Xu…·R.M. Voorhees

The paper identifies FAM136A as a chaperone essential for mitochondrial membrane protein biogenesis, specifically for VDAC paralogs and some electron transport chain subunits.

DOI 10.64898/2026.08.03.742567

humanexperimental assay

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Molecular BiologybioRxivPreprintApr 2, 2026

TXNDC15 modulated quality control at the endoplasmic reticulum shapes ciliogenesis

Vy N. Nguyen, Lena A. K. Bögeholz, Katharine R. Page…·R.M. Voorhees

The paper identifies TXNDC15 as a regulator of ER membrane protein quality control, showing its dual role in modulating MARCHF6 activity and its link to ciliogenesis defects in Meckel-Gruber syndrome.

DOI 10.64898/2026.04.01.715963

humanexperimental assay

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MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedMay 19, 2025

Discovery of lydiamycin A biosynthetic gene cluster in the plant pathogen Rhodococcus fascians guides structural revision and identification of molecular target

Jonathan J. Ford, Javier Santos‐Aberturas, Edward S. Hems…·Andrew W. Truman

The paper identifies a biosynthetic gene cluster in Rhodococcus fascians that produces lydiamycin A, a novel HPS-containing macrocyclic pentapeptide with antibacterial activity against peptide deformylase.

10 citationstop 4%

bacteria (other)metagenomics

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