Molecular BiologybioRxivPreprint
Engineered bacterial M1GS ribozyme efficiently cleaves the most abundant ribosomal RNA in a human cancer cell line
Neha Priyadarshini, Navinchandra Venkatarama Puppala, Harikrishnan Poiyamozhi…·Gireesha Mohannath
The paper develops a tool to predict M1GS ribozyme target sites and demonstrates its efficiency in downregulating 28S rRNA in a human cancer cell line.
DOI 10.1101/2025.11.07.687305