Comparative analysis of Endoxifen, Tamoxifen and Fulvestrant: A Bioinformatics Approach to Uncover Mechanisms of Action in Breast Cancer
H. Lawrence Remmel, Sandra S. Hammer, Harjinder Singh, Anastasia Shneyderman, Alexander Veviorskiy, Khadija M. Alawi, Mikhail Korzinkin, Alex A. Zhavoronkov, Steven C. Quay
This study compares endoxifen, tamoxifen, and fulvestrant using omics data to identify their distinct mechanisms of action in breast cancer, revealing differences in pathway effects and potential therapeutic implications.
bioRxiv · Oct 2, 2024 · PreprintCancer Biology