Joanne Turner

Impact of the elderly lung mucosa on Mycobacterium tuberculosis metabolic adaptation during infection of alveolar epithelial cells

This study shows that elderly lung mucosa alters Mycobacterium tuberculosis gene expression, enhancing its metabolic adaptation and survival in alveolar epithelial cells.

Host- and age-dependent transcriptional changes in Mycobacterium tuberculosis cell envelope biosynthesis genes after exposure to human alveolar lining fluid

This study shows that Mycobacterium tuberculosis alters its cell envelope gene expression in response to human alveolar lining fluid, with differences observed between young and elderly donors.

The aging lung mucosa: A proteomics study

This study identifies neutrophils in elderly lungs as contributors to a dysregulated environment, providing a proteomic baseline for future research on respiratory infection susceptibility.