Whole-genome duplication in the Multicellularity Long Term Evolution Experiment
Kai Tong, Sayantan Datta, Vivian Cheng, Daniella J. Haas, Saranya Gourisetti, Harley L. Yopp, Thomas C. Day, Dung T. Lac, Ahmad S. Khalil, Peter L. Conlin, Gonensin Ozan Bozdag, William C. Ratcliff
This study shows that diploid yeast under selection for larger multicellular size rapidly undergoes spontaneous whole-genome duplication, which persists and facilitates adaptation through increased genetic variation.
Nature · Mar 5, 2025Peer-reviewedEvolutionary Biology