Iterative remodeling of the mouse uterus requires Hedgehog signaling
Elle C. Roberson, Ngan Kim Tran, Anushka N. Godambe, Trinity Rust, Ange Michelle Nguimtsop, Harrison Mark, Rebecca D. Fitch, John B. Wallingford
This study identifies Hedgehog signaling as essential for cyclical uterine remodeling in mice, showing that its disruption prevents remodeling and causes smooth muscle hypertrophy.
bioRxiv · Oct 27, 2022 · PreprintDevelopmental Biology