Lentiviral interleukin-10 gene therapy preserves fine motor circuitry and function after a cervical spinal cord injury in male and female mice
Jessica Y. Chen, Emily J. Fu, Paras R. Patel, Alexander Hostetler, Hasan A. Sawan, Kayla A. Moss, Sarah E. Hocevar, Aileen J. Anderson, Cynthia A. Chestek, Lonnie D. Shea
This study shows that interleukin-10 gene therapy reduces lower motor neuron loss and muscle denervation after spinal cord injury, improving motor function in mice.
Neurotherapeutics · Oct 13, 2020Peer-reviewedNeuroscience