GolpHCat (TMEM87A): a unique voltage-gated and pH-sensitive cation channel in the Golgi
Hyunji Kang, Heejin Jeong, Ah Reum Han, Wuhyun Koh, Jung Moo Lee, Heeyoung Jo, Hayeon Lee, Mridula Bhalla, Woo Suk Roh, Hyun Jun Jang, Boyoung Lee, Ho Min Kim, Hyun Joo An, Changjoon Justin Lee
This study identifies TMEM87A as a novel Golgi-resident cation channel, GolpHCat, which regulates pH homeostasis and is essential for brain function and memory.
bioRxiv · Jan 3, 2023 · PreprintMolecular Biology