Long-read Spatial Transcriptomic Profiling of Patient-derived ccRCC Tumoroids Reveals Heterogeneity in Isoform and Gene Expression
Mustafa Elshani, Hazem Abdullah, Ying Zhang, Alexander Laird, Peter Mullen, David James Harrison
The paper uses long-read spatial transcriptomics on ccRCC tumoroids to reveal gene and isoform expression heterogeneity, identifying distinct functional tumor clusters and isoform-specific patterns.
bioRxiv · Oct 16, 2024 · PreprintCancer Biology