Preconditioning by voluntary wheel running attenuates later neuropathic pain via Nrf2 antioxidant signaling in rats
Suzanne M. Green‐Fulgham, Michael E. Harland, Jayson B. Ball, Jiahe Li, Michael J. Lacagnina, Heather D'Angelo, Renee A. Dreher, Kendal F. Willcox, Sabina A. Lorca, Andrew J. Kwilasz, Steven F. Maier, Linda R. Watkins, Peter M. Grace
This study shows that voluntary wheel running before sciatic nerve injury reduces neuropathic pain in rats by enhancing antioxidant defenses through Nrf2 signaling.
Pain · Jan 24, 2022Peer-reviewedNeuroscience