The shared selection landscape of dog and human cancers
Diane P. Genereux, Kate Megquier, Ross Swofford, Jason Turner-Maier, Michelle E. White, Vista Sohrab, Christopher R. Husted, Heather Gardner, Corrie Painter, Cheryl A. London, Elinor K. Karlsson
This study compares genomic features of dog and human cancers across multiple types, finding widespread shared mutational signatures and genes, suggesting dogs as valuable models for precision oncology.
bioRxiv · Oct 15, 2025 · PreprintCancer Biology