Human co-transcriptional splicing kinetics and coordination revealed by direct nascent RNA sequencing
Heather L. Drexler, Karine Choquet, L. Stirling Churchman
The paper develops nano-COP to study co-transcriptional splicing in human and Drosophila cells, revealing that splicing order is not strictly transcriptional and is influenced by cis-regulatory elements.
bioRxiv · Apr 17, 2019 · PreprintMolecular Biology