Peroxiredoxin-mediated HMGB1 oxidation and secretion in response to inflammatory stimuli
Man Sup Kwak, Hee Sue Kim, Khulan Lkhamsuren, Young Hun Kim, Myung Gil Hahn, Jae Min Shin, In Ho Park, Se Kyung Lee, Sue Goo Rhee, Jeon-Soo Shin
This study shows that peroxiredoxin-mediated oxidation of HMGB1 is necessary for its secretion during inflammation.
bioRxiv · Feb 1, 2018 · PreprintImmunology