Micro-Cm: restrictase-free microbiome-wide chromosome conformation profiling
Marcos Bermejo Ruiz, Carolin Wilhelm, Heike Budde, Ruth E. Ley, Alexander Tyakht
The paper introduces Micro-Cm, a restrictase-free method for microbiome-wide chromosome conformation profiling, showing improved plasmid-host association detection in simulated and real gut microbiome samples.
bioRxiv · Sep 12, 2026 · PreprintMicrobiology