Author

Helen Byers

Manchester Academic Health Science Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genetics· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Assay:GWAS summary statistics· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. Gareth EvansiD· 3 shared Alison M. DunningiD· 2 shared Christopher A. HaimaniD· 2 shared Diana EcclesiD· 2 shared Fergus J. CouchiD· 2 shared Glenda M. BeamaniD· 2 shared Hermann BrenneriD· 2 shared Irene Louise AndrulisiD· 2 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersGenetics

D. Gareth EvansORCID

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Author profile →

4 papers

Recent·Most cited

PRANA: A Deep Learning Method for Adapting Polygenic Risk Scores to Diverse Ethnic Groups

Hagai Levi, Qin Wang, Manjeet K. Bolla, Joe Dennis, Irene L. Andrulis, Natalia Antonenkova, Chun Hang Au, Annelie Augustinsson, Laura E. Beane Freeman, Sabine Behrens, Marina Bermisheva, Clara Bodelón, Natalia Viktorovna Bogdanova, Stig E. Bojesen, Hermann Brenner, , Kyriaki Michailidou

PRANA adapts polygenic risk scores to non-European populations, improving predictive accuracy by 5%-20% in South Asian, East Asian, and Ashkenazi Jewish populations.

medRxiv · Jul 15, 2026 · PreprintGenetic & Genomic Medicine

Genetic Risk of Axonal Neuropathy Following Infection

J. Robert Harkness, John Henry McDermott, Shea Marsden, Peter Jamieson, Kay Metcalfe, Naz Khan, William L. Macken, Robert D. S. Pitceathly, Christopher J. Record, Reza Maroofian, Kloepa Kloepas, Ataf Hussain Sabir, Lily Islam, Saikat Santra, Enise Avcı Durmuşalioğlu, , William G. Newman

The paper identifies biallelic RCC1 variants causing an acute axonal neuropathy triggered by infection, with mechanistic overlap with ALS and GBS.

medRxiv · Oct 4, 2024 · PreprintGenetic & Genomic Medicine

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

Haoyu Zhang, Thomas U. Ahearn, Julie Lecarpentier, Daniel R. Barnes, Jonathan Beesley, Xia Jiang, Tracy A. O’Mara, Guanghao Qi, Ni Zhao, Manjeet K. Bolla, Alison M. Dunning, Joe Dennis, Qin Wang, Zumuruda Abu Ful, Kristiina Aittomäki, , Peter Hillemanns

This study identifies 32 new breast cancer susceptibility loci through GWAS, with associations varying by tumor subtype and genetic correlations among subtypes.

Nature Genetics · May 18, 2020Peer-reviewedGenetics

Inherited BRCA1 epimutation as a novel cause of breast and ovarian cancer

D. Gareth Evans, Elke Maria van Veen, Helen Byers, Andrew J. Wallace, Jamie M. Ellingford, Glenda M. Beaman, Javier Santoyo‐López, Timothy J. Aitman, Diana Eccles, Fiona I. Lalloo, Miriam Jane Smith, William G. Newman

The paper identifies inherited BRCA1 promoter hypermethylation as a novel cause of breast and ovarian cancer in two families without germline BRCA1/2 pathogenic variants.

bioRxiv · Jan 18, 2018 · PreprintGenetics