Differential D1 and D2 receptor internalization and recycling induced by amphetamine in vivo
Hanne Demant Hansen, Martin Schain, Helen P. Deng, Joseph B. Mandeville, Bruce Robert Rosen, Christin Y.M. Sander
This study shows that amphetamine differentially affects D1R and D2R internalization and recycling in nonhuman primates, with D1R showing excitatory signaling and D2R remaining internalized after repeated administration.
bioRxiv · Jun 10, 2022 · PreprintNeuroscience