Cardiac fibrosis inhibitor CTPR390 prevents structural and morphological changes in collagen and fibroblasts of engineered human connective tissue
David Maestro, Ana Palanca, Helena Soto, Irantzu Llarena, Alisa Nicole DeGrave, Gabriela Guedes, Guilherme Oliveira, André Luiz Coelho Conceição, Verónica Mieites, Jose Manuel Icardo, Carlos Sánchez-Cano, Olga M. Conde, Susanne Lutz, Aitziber L. Cortajarena, Ana Victoria Villar
This study shows that CTPR390 prevents structural and morphological changes in collagen and fibroblasts in a 3D human cardiac model.
bioRxiv · Jan 15, 2025 · PreprintBiochemistry