Systems biology analysis of mitogen activated protein kinase inhibitor resistance in malignant melanoma
Helma Zecena, Daniel Myklatun Tveit, Zi Wang, Ahmed Majid Farhat, Parvita Panchal, Jing Liu, Simar J. Singh, Amandeep Sanghera, Ajay Bainiwal, Shuan Y. Teo, Frank Louis Meyskens, Feng Liu, Fabian V. Filipp
The paper establishes an in vitro model of MAPK inhibitor resistance in melanoma and identifies transcriptional changes and pathways involved in resistance mechanisms.
BMC Systems Biology · Apr 3, 2018Peer-reviewedSystems Biology