Interleukin-17A Secreted from the Lung-infiltrating T Helper 17 Cells Renders Protective Immunity to Pulmonary Cryptococcus neoformans Infection
Elaheh Movahed, Grace Min Yi Tan, Heng Choon Cheong, Chalystha Yie Qin Lee, Yi Ying Cheok, Sun Tee Tay, Pei Pei Chong, Won Fen Wong, Chung Yeng Looi
This study shows that IL-17A secreted by lung-infiltrating T helper 17 cells protects against Cryptococcus neoformans infection by reducing fungal burden and improving survival.
bioRxiv · May 23, 2018 · PreprintImmunology