The mechanism of ribosomal recruitment during translation initiation on Type 2 IRESs
Sayan Bhattacharjee, Irina S. Abaeva, Zuben P. Brown, Yani Arhab, Hengameh Fallah, Christopher U.T. Hellen, Joachim Frank, Tatyana V. Pestova
The paper determines the cryo-EM structure of 48S initiation complexes on EMCV IRESs and identifies key interactions essential for ribosomal recruitment.
bioRxiv · Jun 11, 2025 · PreprintMolecular Biology