Zuben P. Brown

Structural Studies of Nedicistrovirus IRES-Driven, Initiation Factor-independent Translation Shed Light on Key Steps of Eukaryotic Translation Elongation

The paper determines high-resolution structures of NediV IRES-mediated translation initiation complexes and their transition to elongation, revealing structural changes and interactions during viral translation.

The mechanism of ribosomal recruitment during translation initiation on Type 2 IRESs

The paper determines the cryo-EM structure of 48S initiation complexes on EMCV IRESs and identifies key interactions essential for ribosomal recruitment.

Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering

The paper identifies inconsistencies in rabbit ribosomal rRNA sequences and proposes using the Broad Institute's genome sequence to standardize numbering and improve model consistency.

Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA

The paper presents cryo-EM structures of Hepatitis C virus IRES initiation complexes, revealing conformational changes during translation initiation.