Author

Henry R. Saltzman

Massachusetts General Hospital

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

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Christiano R. R. AlvesiD· 1 shared Dadi GaoiD· 1 shared Elisabetta MoriniiD· 1 shared Hannah Lindmeier· 1 shared Henry Shull· 1 shared Huilin XuiD· 1 shared M. Catarina SilvaiD· 1 shared Melissa Anne WalkeriD· 1 shared

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Christiano R. R. AlvesORCID

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1 paper

Recent·Most cited

Poison exon splicing in the human brain: a new paradigm for understanding and targeting neurological disorders

Paolo Pigini, Huilin Xu, Yan Ji, Hannah Lindmeier, Henry R. Saltzman, Henry Shull, Shuqi Yun, Christiano R. R. Alves, Melissa Anne Walker, M. Catarina Silva, Dadi Gao, Elisabetta Morini

The paper identifies 9,814 poison exons in the human genome, finds brain-specific splicing patterns, and links pathogenic variants to PE splicing affecting neurological disorders.

bioRxiv · Jun 26, 2025 · PreprintGenetics