Author

Hannah Lindmeier

Massachusetts General Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Elisabetta MoriniiD· 2 shared M. Catarina SilvaiD· 2 shared Paolo PiginiiD· 2 shared Angela Minnella· 1 shared Christiano R. R. AlvesiD· 1 shared Christie MorrilliD· 1 shared Christopher R. TrottaiD· 1 shared Dadi GaoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetics

Elisabetta MoriniORCID

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2 papers

Recent·Most cited

Poison exon splicing in the human brain: a new paradigm for understanding and targeting neurological disorders

Paolo Pigini, Huilin Xu, Yan Ji, Hannah Lindmeier, Henry R. Saltzman, Henry Shull, Shuqi Yun, Christiano R. R. Alves, Melissa Anne Walker, M. Catarina Silva, Dadi Gao, Elisabetta Morini

The paper identifies 9,814 poison exons in the human genome, finds brain-specific splicing patterns, and links pathogenic variants to PE splicing affecting neurological disorders.

bioRxiv · Jun 26, 2025 · PreprintGenetics

MAPT Splicing Modulators as a Therapeutic Strategy for Tauopathies

M. Catarina Silva, Hannah Lindmeier, Paolo Pigini, Jennifer Laughlin, Yong Yu, Christie Morrill, Michael A. Arnold, Scott J. Barraza, Khalil Saadipour, Monal Dieterich, Angela Minnella, Kausiki Datta, Nanjing Zhang, Jana Narasimhan, Christopher R. Trotta, , Elisabetta Morini

Discovery of SMCs that correct MAPT splicing, reduce 4R tau, and rescue pathology in patient-derived neuronal and in vivo models of 4R tauopathies.

bioRxiv · May 6, 2025 · PreprintNeuroscience