Author

Henry Silvernail

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Biology Disciplines

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Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Organism:human· 1 Assay:protein structure· 1 Assay:proteomics· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

Wangfei YangiD· 2 shared Wenwei ZhengiD· 2 shared Debasis SahaiD· 1 shared Eleni PanagiotouiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersBiophysics

Wangfei YangORCID

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2 papers

Recent·Most cited

Hydrophobic Patch Spacing Produces Nonmonotonic Compaction in Intrinsically Disordered Proteins

Henry Silvernail, Wangfei Yang, Wenwei Zheng

This study shows that hydrophobic patch spacing in IDPs leads to nonmonotonic compaction, depending on interaction strength and architecture.

bioRxiv · Sep 4, 2026 · PreprintBiophysics

Topological Entanglement in Intrinsically Disordered Proteins: Sequence, Structural, and Functional Determinants

Wangfei Yang, Henry Silvernail, Debasis Saha, Eleni Panagiotou, Wenwei Zheng

The paper uses entanglement measures from knot theory to analyze sequence and structural features of intrinsically disordered proteins and identifies functionally enriched regions in entanglement space.

The Journal of Physical Chemistry B · Jun 24, 2026Peer-reviewedBiophysics