Author

Debasis Saha

Arizona State UniversityORCID 0000-0002-7461-0026Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:human· 1 Assay:long-read sequencing· 1 Assay:proteomics· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

Wangfei YangiD· 2 shared Wenwei ZhengiD· 2 shared Eleni PanagiotouiD· 1 shared Henry Silvernail· 1 shared Jinghui LuoiD· 1 shared Xun SuniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersBiophysics

Wangfei YangORCID

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2 papers

Recent·Most cited

Topological Entanglement in Intrinsically Disordered Proteins: Sequence, Structural, and Functional Determinants

Wangfei Yang, Henry Silvernail, Debasis Saha, Eleni Panagiotou, Wenwei Zheng

The paper uses entanglement measures from knot theory to analyze sequence and structural features of intrinsically disordered proteins and identifies functionally enriched regions in entanglement space.

The Journal of Physical Chemistry B · Jun 24, 2026Peer-reviewedBiophysics

Residue-Specific Modulation of Aggregation-Associated Interactions bySpermine in Tau, α-Synuclein, and Aβ40

Debasis Saha, Xun Sun, Wangfei Yang, Jinghui Luo, Wenwei Zheng

This study shows how spermine modulates aggregation of Tau, α-synuclein, and Aβ40 by residue-specific interactions, revealing that net charge alone cannot predict its effects.

JACS Au · Mar 12, 2026Peer-reviewedBiophysics