Leveraging structurally-informed bioorthogonal conjugation for alpha synuclein fibril surveillance
Rebecca A. Jenkins, Samantha Wu, Cameron W. Flowers, Lily J. Taylor, Gretchen Fujimura, Heredia Andres, Chuanqi Sun, Michael R. Sawaya, Joseph A. Loo, José A. Rodríguez
This paper develops a method to label alpha synuclein fibrils with fluorophores for tracking their structure and function in cells.
bioRxiv · Sep 12, 2025 · PreprintBiochemistry