Dlk1-Dio3 Locus-Derived LncRNAs Perpetuate Postmitotic Motor Neuron Cell Fate and Subtype Identity
Ya-Ping Yen, Wen-Fu Hsieh, Ya-Yin Tsai, Ya-Lin Lu, Ee Shan Liau, Ho-Chiang Hsu, Yen‐Chung Chen, Ting-Chun Liu, Mien Chang, Joye Li, Shau‐Ping Lin, Jui‐Hung Hung, Jun‐An Chen
This study identifies lncRNAs from the Dlk1-Dio3 locus that maintain postmitotic motor neuron fate and subtype identity by regulating H3K27me3 and Hox gene expression.
eLife · Oct 12, 2018Peer-reviewedDevelopmental Biology