Author

Ya-Yin Tsai

Stowers Institute for Medical ResearchORCID 0000-0002-9152-7646Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 5

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:zebrafish· 4 Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:clustering· 1

Frequent Co-Authors

Mark E. LushiD· 4 shared Tatjana PiotrowskiiD· 4 shared Jeremy E. SandleriD· 2 shared Julia PeloggiaiD· 2 shared Nhung T. T. TraniD· 2 shared Shiyuan CheniD· 2 shared Abhinav SuriD· 1 shared Allison R. ScottiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersDevelopmental Biology

Mark E. LushORCID

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5 papers

Recent·Most cited

prdm1a drives a fate switch between hair cells of different mechanosensory organs

Jeremy E. Sandler, Ya-Yin Tsai, Shiyuan Chen, Logan Sabin, Mark E. Lush, Abhinav Sur, Elizabeth Ellis, Nhung T. T. Tran, Malcolm E. Cook, Allison R. Scott, Jonathan S. Kniss, Jeffrey A. Farrell, Tatjana Piotrowski

This study shows prdm1a drives a fate switch between zebrafish lateral line and ear hair cells, altering morphology and transcriptome.

Nature Communications · Aug 18, 2025Peer-reviewedDevelopmental Biology

Stem and progenitor cell proliferation are independently regulated by cell type-specific cyclinD genes

Mark E. Lush, Ya-Yin Tsai, Shiyuan Chen, Daniela Münch, Julia Peloggia, Jeremy E. Sandler, Tatjana Piotrowski

The paper shows that cyclinD genes regulate stem and progenitor cell proliferation in zebrafish lateral line sensory organs through cell type-specific mechanisms.

Nature Communications · Jul 14, 2025Peer-reviewedDevelopmental Biology

Environmental and molecular control of tissue-specific ionocyte differentiation in zebrafish

Julia Peloggia, Mark E. Lush, Ya-Yin Tsai, Christopher Wood, Tatjana Piotrowski

The paper identifies how environmental changes trigger the differentiation of skin cell progenitors into Nm ionocytes in zebrafish, showing their response to specific ion levels and hair cell activity.

Development · Sep 26, 2024Peer-reviewedDevelopmental Biology

High-resolution single cell transcriptome analysis of zebrafish sensory hair cell regeneration

Sungmin Baek, Nhung T. T. Tran, Daniel C. Diaz, Ya-Yin Tsai, Joaquín Navajas Acedo, Mark E. Lush, Tatjana Piotrowski

This study uses scRNA-Seq to analyze zebrafish hair cell regeneration, identifying three sequential transcriptional modules involved in the process.

bioRxiv · Jul 15, 2021 · PreprintDevelopmental Biology

Dlk1-Dio3 Locus-Derived LncRNAs Perpetuate Postmitotic Motor Neuron Cell Fate and Subtype Identity

Ya-Ping Yen, Wen-Fu Hsieh, Ya-Yin Tsai, Ya-Lin Lu, Ee Shan Liau, Ho-Chiang Hsu, Yen‐Chung Chen, Ting-Chun Liu, Mien Chang, Joye Li, Shau‐Ping Lin, Jui‐Hung Hung, Jun‐An Chen

This study identifies lncRNAs from the Dlk1-Dio3 locus that maintain postmitotic motor neuron fate and subtype identity by regulating H3K27me3 and Hox gene expression.

eLife · Oct 12, 2018Peer-reviewedDevelopmental Biology