Multidimensional atlas of RNA-regulated proteins revealed by RNA-dependent thermal proteome profiling
Yongzuo Chen, Zeyu Liu, Yankun Wang, W P Lu, Hui Li, Wenjing Wang, Zhili Qiu, Yunjie Qiu, Hong Qing, Y D Xie, Nian Liu, Conggang Zhang, Ying Chen, Wei Qin
This paper introduces RTPP to identify RNA-regulated proteins and generates a tissue-specific atlas of RNA-protein interactions, revealing novel orphan proteins and organ-specific dysregulation in Alzheimer's disease.
bioRxiv · Jul 16, 2026 · PreprintMolecular Biology