Covalent tumor anchoring spatially orchestrates antitumor immunity
Qingke Li, Hongfei Chen, Pan Zhang, Li Cao, Bingchen Yu, Lei Wang
This paper introduces CATIPs, covalently anchored tumor immunotherapeutic proteins that enhance antitumor immunity by immobilizing immune cues on tumor surfaces, showing improved efficacy and reduced toxicity in preclinical models.
bioRxiv · May 14, 2026 · PreprintSynthetic Biology