Author

Hsin-Feng Chang

Biodiversity Research Center, Academia Sinica

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Organism:non-human primate· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Po‐Shun ChuangiD· 3 shared Kai-Ning Shih· 2 shared Mo CheniD· 2 shared Sen‐Lin TangiD· 2 shared Sheng-Ping YuiD· 2 shared Yen Jui-Hung· 2 shared Yi-Ren Chang· 2 shared Chih-Ying LuiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMicrobiology

Po‐Shun ChuangORCID

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3 papers

Recent·Most cited

Integrated transcriptomic and metabolite analyses link DMSP cleavage to acetate overflow in the coral symbiont Endozoicomonas ruthgatesiae

Ying-Chieh Chen, Yen Jui-Hung, Ting‐Chang Hsu, Wan-Ting Liao, Hsin-Feng Chang, Chih‐Ying Lu, Li-Rong Lin, Sen‐Lin Tang, Po‐Shun Chuang

This study links DMSP cleavage to acetate overflow in the coral symbiont Endozoicomonas ruthgatesiae under different temperature conditions.

bioRxiv · Oct 8, 2026 · PreprintMicrobiology

Microbial profiling and single-cell transcriptomics reveal probiotic mechanisms of coral thermal resilience

Chih-Ying Lu, Yi-Ren Chang, Victor M. Piñón-González, Thomas D. Lewin, Kai-Ning Shih, Po‐Shun Chuang, Naohisa Wada, Sheng-Ping Yu, Zhao-Rong Yu, Yi-Hua Chen, Mo Chen, Ching‐Hsiang Chin, Yu‐Jing Chiou, Yi‐Ling Chiu, Isabel Jiah-Yih Liao, , Sen‐Lin Tang

This study identifies E. acroporae Acr-14T as a coral probiotic that enhances thermal resilience by mitigating protein-folding stress and supporting energy homeostasis through single-cell transcriptomics and microbial profiling.

The ISME Journal · Jan 1, 2026Peer-reviewedMicrobiology

Bacteriophages of the predominant coral symbiont Endozoicomonas: novel models for coral holobiont interactions

Po‐Shun Chuang, Mo Chen, Pei‐Wen Chiang, Hsing‐Ju Chen, Feng-Chi Wang, Yu‐Hsiang Chen, Sheng-Ping Yu, Fu-Chi Chen, Kai-Ning Shih, Yi-Ren Chang, Sim Lin Lim, Hsin-Feng Chang, Wann‐Neng Jane, Sen-Lin Tang

The paper isolates and characterizes two novel bacteriophages infecting the coral symbiont Endozoicomonas, revealing their potential role in coral holobiont interactions.

bioRxiv · Oct 29, 2025 · PreprintMicrobiology