Deregulation of the histone H3K9 dimethylation landscape suppresses Wnt signaling in embryonal rhabdomyosarcoma
Ananya Pal, Jia Yu Leung, Gareth Chin Khye Ang, Vinay Kumar Rao, Luca Pignata, Huey Jin Lim, Maxime Hebrard, Kenneth Tou En Chang, Victor Kwan Min Lee, Ernesto Guccione, Reshma Taneja
This study shows that G9a inhibition reduces DKK1 expression and enhances Wnt signaling, promoting myogenic differentiation in ERMS cells.
bioRxiv · Apr 20, 2020 · PreprintMolecular Biology