The TRPC6-AMPK pathway is involved in cytoskeleton reorganization and glucose uptake in podocytes.
P. Rachubik, M. Szrejder, D. Rogacka, I. Audzeyenka, M. Rychłowski, S. Angielski, A. Piwkowska
The paper investigates the role of the TRPC6-AMPK pathway in insulin-dependent cytoskeleton reorganization and glucose uptake in cultured rat podocytes, finding it regulates these processes through Rac1 signaling.
bioRxiv · Mar 8, 2018Cell Biology