PathologybioRxiv
Deletion of Mcpip1 in Mcpip1AlbKO mice recapitulates the phenotype of human primary biliary cholangitis
J. Kotlinowski, T. Hutsch, I. Czyzynska-Cichon…·S. Chlopicki
This paper shows that deleting Mcpip1 in liver-specific mice (Mcpip1AlbKO) causes a PBC-like disease, with features similar to human primary biliary cholangitis, including fibrosis, inflammation, and autoantibodies.
DOI 10.1016/j.bbadis.2021.166086